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Research Examining the Benefits of Stem Cell Therapy for Covid-19 Treatment

JawaPos.com – Stem cell therapy has recently become increasingly popular for both medicine and beauty. Now, researchers are also developing stem cell research for the treatment of Covid-19.

In the webinar, PT Kalbe Farma Tbk (Kalbe) collaborates with the Ministry of Research and Technology / National Research and Innovation Agency (Kemenristek / BRIN) in Research and Technology / BRIN Kalbe Science Awards (RKSA) 2021 with the theme Downstream Research to Nourish the Nation, provide research funding for researchers in Indonesia with the theme of health, pharmacy, functional food, information technology or life science.

“It is the result of the collaboration between the Ministry of Research and Technology / National Agency for Research and Technology and Kalbe to strengthen collaboration between academics, business and government as well as other research communities to increase the downstreaming of research in the health sector. Downstream research will contribute positively to improving health services for the community and increasing national economic value. As well as paying special attention to research related to Covid-19, “said the Director of PT Kalbe Farma Tbk. Sie Djohan, in a recent webinar.

Also Read: Stem Cell Therapy Was Developed To Prevent Death In Covid-19 Patients

The role of stem cell research in the development of treatment, especially in the face of the Covid-19 pandemic, was researched by Chief Scientific Officer of Kalbe Genexine Biologics, Yulius Setiady and Chairman of Rejaselindo as well as Research Coordinator for Umbilical Cord Mesenchymal Stem Cell Research on Covid-19 Degrees of Weight, Dr. dr. Bintang Soetjahjo Sp OT (K). As well as the Chairperson of Central Java PABOI and Head of KSM Orthopedic Traumatology Hospital Dr. Moewardi.

Yulius Setiady said that therapeutic discoveries against disease require a long, complex and laborious effort. The more we know about the biology of disease, the greater the opportunity to develop good medicine. The diagnostic, difficult-to-predict role of the immune system in the pre-clinical setting is also indispensable in the therapeutic development under investigation and should not be underestimated.

Meanwhile, researcher Bintang Soetjahjo added that ability Mesenchymal stem cell (MSC) to regenerate and differentiate makes cells a promising therapeutic agent for Covid-19. Various studies have begun to attract the attention of world scientists to make MSC the standard therapy for Covid-19 cases. However, he believes that with the support of experts, scientists, and the Indonesian people, this cell-based treatment is able to contribute to the management of Covid-19 patients in Indonesia.

What are stem cells?

Stem cells can regenerate themselves through division. Even after being inactive for a period
which is old. Stem cells can come from both animals and humans. Embryonic and non-
somatic embryonic or adult stem cells, under physiological or experimental conditions, stem cells can be induced to become specific tissue cells or organs with special functions. In the intestines and bone marrow, stem cells can repair themselves periodically and replace damaged tissue.

“This treatment has been proven to play a role in curing various diseases. Various studies have shown that the anti-inflammatory effect of MSCs can significantly reduce viral lung injury and death in mice, “said the researchers.

Stem cells significantly reduced acute lung injury in mice caused by the H9N2 and H5N1 viruses by reducing levels of proinflammatory cytokines and chemokines and reducing inflammation into the lungs. These findings emphasize that stem cell-based treatment in principle makes use of the immunomodulating and regenerating abilities of stem cells

“In studies, stem cells can significantly reduce lung pathological changes and inhibit cell-mediated immune inflammatory responses.”

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Editor: Nurul Adriyana Salbiah

Reporter: Marieska Harya Virdhani